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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAT1A All Species: 33.03
Human Site: S170 Identified Species: 48.44
UniProt: Q00266 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00266 NP_000420.1 395 43648 S170 R M A D L R R S G L L P W L R
Chimpanzee Pan troglodytes XP_515585 413 45605 N170 K L A E L R R N G T L P W L R
Rhesus Macaque Macaca mulatta XP_001087977 396 43707 S171 R M A D L R R S G L L P W L R
Dog Lupus familis XP_851933 396 43499 S171 R M A D L R R S G V L P W L R
Cat Felis silvestris
Mouse Mus musculus Q91X83 396 43490 S171 R I A D L R R S G V L P W L R
Rat Rattus norvegicus P13444 397 43679 S171 R M A D L R R S G V L P W L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421512 396 43734 S171 R L A E L R R S G E L P W L R
Frog Xenopus laevis NP_001080175 396 43767 N171 K M A E L R R N G T L P W L R
Zebra Danio Brachydanio rerio NP_956165 390 43271 D165 K M A E L R R D G T I P W L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40320 408 44678 S181 K I A E L R R S D V F W W A R
Honey Bee Apis mellifera XP_623669 404 44652 S178 K I A E L R R S G E L W W A R
Nematode Worm Caenorhab. elegans P50305 404 44016 S158 K L H E L R R S G E L E W V R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa A9P822 392 43195 N158 R L T E V R K N G T C P W L R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LUT2 393 42777 N158 K L T E V R K N G T C P W L R
Baker's Yeast Sacchar. cerevisiae P10659 382 41800 D157 A M A D A R R D G S L A W L R
Red Bread Mold Neurospora crassa P48466 395 42967 D169 A M S A A R R D G S L P W L R
Conservation
Percent
Protein Identity: 100 80.1 98.2 95.9 N.A. 96.2 95.7 N.A. N.A. 90.9 84.8 82.2 N.A. 68.6 70.5 68.3 N.A.
Protein Similarity: 100 88.6 99.2 98.4 N.A. 98.4 98.4 N.A. N.A. 96.4 92.9 92.6 N.A. 85.5 86.3 83.1 N.A.
P-Site Identity: 100 66.6 100 93.3 N.A. 86.6 93.3 N.A. N.A. 80 73.3 66.6 N.A. 46.6 60 53.3 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. N.A. 93.3 93.3 86.6 N.A. 73.3 80 80 N.A.
Percent
Protein Identity: 61 N.A. N.A. 60.7 66.5 68.1
Protein Similarity: 75.9 N.A. N.A. 77.4 81.2 82.7
P-Site Identity: 46.6 N.A. N.A. 40 66.6 60
P-Site Similarity: 80 N.A. N.A. 80 66.6 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 75 7 13 0 0 0 0 0 0 7 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 0 0 0 38 0 0 0 19 7 0 0 0 0 0 0 % D
% Glu: 0 0 0 57 0 0 0 0 0 19 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 94 0 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 19 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 44 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % K
% Leu: 0 32 0 0 75 0 0 0 0 13 75 0 0 82 0 % L
% Met: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 44 0 0 0 0 100 88 0 0 0 0 0 0 0 100 % R
% Ser: 0 0 7 0 0 0 0 57 0 13 0 0 0 0 0 % S
% Thr: 0 0 13 0 0 0 0 0 0 32 0 0 0 0 0 % T
% Val: 0 0 0 0 13 0 0 0 0 25 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 13 100 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _